Avycaz (ceftazidime/avibactam) Patient Assistance Program
Don’t let the high cost of brand ceftazidime-avibactam disrupt your resistant gram-negative infection treatment. We help eligible patients access Avycaz (ceftazidime + avibactam IV) for as little as $69.95 per month through the manufacturer’s Patient Assistance Program.
- Clear & Transparent Pricing
- Paperwork & Doctor-Coordination
- Comprehensive Support: From Application to Entire Journey
- Annual Re-certification And Refills Management
- Medicare Part D Patients Accepted
Key Takeaways:
- Avycaz (ceftazidime/avibactam) is FDA-approved for complicated intra-abdominal infections (with metronidazole), complicated urinary tract infections including pyelonephritis, and hospital-acquired or ventilator-associated bacterial pneumonia caused by susceptible gram-negative bacteria including KPC-producing Enterobacterales. Beta-lactam / beta-lactamase inhibitor combination.
- Without assistance, Avycaz costs commonly run approximately $700–$1,200 per dose (multiple doses daily).
- Through AffordMyPrescriptions, qualifying patients can access Avycaz for a flat $69.95 per month coverage.
- Other resistant gram-negative antibiotics: Zerbaxa (ceftolozane/tazobactam), Vabomere (meropenem/vaborbactam), Recarbrio (imipenem/cilastatin/relebactam), Fetroja (cefiderocol), Xerava (eravacycline), Emblaveo (aztreonam/avibactam — 2025 approval for MBL producers), colistin/polymyxin B (generic — nephrotoxic reserve). Avycaz is active against KPC producers but NOT metallo-beta-lactamase producers. Culture and sensitivity testing essential. ID consultation recommended.
What is Avycaz Prescription Assistance Program?
The Avycaz Patient Assistance Program is a manufacturer-sponsored initiative that helps eligible patients access Avycaz for resistant gram-negative infections at little or no cost when meeting income, insurance, and clinical criteria. The program is free to apply for, but involves detailed applications, infectious disease coordination, culture/sensitivity documentation, and ongoing renewal.
At AffordMyPrescriptions, our Patient Advocates handle the entire Avycaz PAP enrollment for a flat $69.95 per month — application, prescriber coordination, manufacturer follow-up, refill management, and annual re-certification — so you never face a gap in Avycaz therapy.
AffordMyPrescriptions eliminates that burden. For a flat $69.95 per month, our Patient Advocates handle every step of your Avycaz enrollment — so you never face a gap in your resistant gram-negative infection treatment.
Pharmacy Price Comparison
- Without assistance, Avycaz costs hundreds of dollars per dose at hospitals. A Patient Assistance Program can offset costs if you qualify:
| PHARMACY | PRICE (30-DAY) WITH BEST COUPONS | YOU SAVE W/ US |
|---|---|---|
| Generic colistin (reserve) | ~$150/dose | Nephrotoxic reserve alt |
| Hospital pharmacy | ~$1,200/dose | Save substantially |
| Community hospital | ~$1,000/dose | Save substantially |
| Specialty pharmacy | ~$800/dose | Save substantially |
| 340B-eligible institution | ~$700/dose | Save substantially |
| Zerbaxa (alt gram-neg) | ~$500/dose | Alt beta-lactam combo |
*Retail prices are estimates based on public data and vary by pharmacy. Coupon prices from GoodRx and SingleCare as of April 2026. AffordMyPrescriptions Advocacy Service bypasses pharmacy pricing entirely by using the manufacturer’s assistance program to secure your Avycaz — independent of dosage or retail price.
Our Pricing:
$69.95 Per month
1 Medications
$79.95 Per Month
2 Medications
$89.95 Per Month
3 Medications
$99.95 Per Month
4+ Medications
Why choose us For Your Avycaz Prescription Program?
The Avycaz Patient Assistance Program is free to apply and provides medication at no cost if approved. Our $69.95 per month covers full advocacy: applications, prescriber coordination, hospital administration, refill management, and re-enrollment. Culture-directed therapy is essential — Avycaz is active against KPC-producing Enterobacterales but not against metallo-beta-lactamase producers.
Enroll
Complete a simple eligibility form so our team can determine if you may qualify for Avycaz assistance.
We Advocate
Our specialists gather documentation, complete applications, and coordinate with your prescriber and the assistance program.
Receive Medication
Once approved, your Avycaz is delivered through the assistance program while we manage refills and annual renewals.
Discount Coupons vs. Patient Assistance Programs
Many patients try discount cards first. Here’s why the Patient Assistance Program through AffordMyPrescriptions is the better long-term solution for Avycaz:
Limitations of Coupons
Prices fluctuate — savings aren’t guaranteed month-to-month
Copay accumulators may prevent savings from counting toward your deductible
Coupon cards expire and require constant renewal
Still $700–$1,200/dose even with the best discount
Cannot be used with Medicare, Medicaid, or government insurance
Advantages of PAP Through Us
Fixed $69.95/month — never changes regardless of retail price
- No expiration — continuous access as long as you qualify
Medication supplied directly through the assistance program
We manage all paperwork, refills, and annual renewals
Medicare Part D patients accepted
If denied, we explore alternative savings paths on your behalf
DO YOU QUALIFY?
Eligibility is generally determined by annual household income and insurance status. Most programs follow guidelines that include limits of up to $40,000 for individuals, $60,000 for couples, and $100,000 for larger families. Because requirements vary by program and household, we encourage you to contact AffordMyPrescriptions directly so we can review your specific situation and determine if you qualify for Avycaz assistance.
- You Are A U.S. Citizen Or Legal Resident
- You Have A Valid Avycaz Prescription From A Licensed U.S. Healthcare Provider
- You Are Uninsured, Underinsured, Or A Medicare Part D Beneficiary
- You Have Recently Experienced A Change In Financial Circumstances That Affects Your Ability To Pay
Understanding Avycaz:
Avycaz combines ceftazidime (third-generation cephalosporin) with avibactam (non-beta-lactam beta-lactamase inhibitor) — restoring activity against class A (including KPC), class C, and some class D beta-lactamases. A critical option for KPC-producing carbapenem-resistant Enterobacterales (CRE).
How It Works:
Multidrug-resistant gram-negative bacteria produce beta-lactamases that inactivate beta-lactam antibiotics. KPC (Klebsiella pneumoniae carbapenemase) is a major cause of carbapenem-resistant Enterobacterales (CRE) — historically with limited treatment options. Avibactam is a novel non-beta-lactam beta-lactamase inhibitor that covalently but reversibly inhibits class A (including KPC), class C, and some class D (OXA-48) beta-lactamases. Combined with ceftazidime, it restores activity against KPC producers. It does NOT inhibit metallo-beta-lactamases (MBLs — VIM, IMP, NDM). Emblaveo (aztreonam/avibactam) covers MBL producers.
Form and Use:
Avycaz 2.5 g (ceftazidime 2 g + avibactam 0.5 g) IV every 8 hours over 2 hours. Renal dose adjustment. Duration 5–14 days depending on infection. Culture-directed use — reserve for confirmed or highly suspected resistant gram-negative infection. Metronidazole added for complicated intra-abdominal infections (anaerobic coverage).
Generic Availability:
No generic Avycaz. Other resistant gram-negative antibiotics: Zerbaxa (ceftolozane/tazobactam — Pseudomonas coverage, no KPC), Vabomere (meropenem/vaborbactam — KPC coverage), Recarbrio (imipenem/cilastatin/relebactam — KPC coverage), Fetroja (cefiderocol — broad including MBL producers), Xerava (eravacycline), Emblaveo (aztreonam/avibactam — 2025 FDA-approved for MBL producers), colistin (polymyxin E generic — nephrotoxic reserve), polymyxin B, tigecycline generic, fosfomycin. Culture and sensitivity testing essential.
Warnings:
Serious hypersensitivity reactions including anaphylaxis (contraindicated with beta-lactam allergy), CNS effects (seizures at higher doses in renal impairment), C. difficile-associated diarrhea (severe possible), development of resistance (use for confirmed susceptibility), embryo-fetal considerations. Other: elevated LFTs, cytopenias, positive Coombs test, GI effects, headache, dizziness. Nephrotoxicity less than colistin. Drug interactions minimal. Renal dose adjustment essential.
FAQ (Frequently Asked Questions)
How much does Avycaz cost without insurance?
$700–$1,200 per dose — with typical 3-doses-per-day dosing, costs $2,000–$4,000/day, and full courses $10,000–$40,000+ depending on duration. Specialty pharmacy and Patient Assistance Programs are essential.
What is the difference between Avycaz and other novel gram-negative antibiotics?
Different beta-lactam / beta-lactamase inhibitor combinations with different resistance coverage. Avycaz covers KPC-producing Enterobacterales. Zerbaxa is Pseudomonas-focused (no KPC). Vabomere and Recarbrio cover KPC. Fetroja is broad including MBL producers. Emblaveo (2025) is aztreonam/avibactam for MBL producers. Choice depends on culture/sensitivity results.
Why doesn't Avycaz cover metallo-beta-lactamase producers?
Metallo-beta-lactamases (MBLs — VIM, IMP, NDM) are zinc-dependent enzymes with a different mechanism from KPC. Avibactam does not inhibit MBLs. For MBL producers, Fetroja (cefiderocol) or Emblaveo (aztreonam/avibactam — 2025 approval) are options. Colistin remains a reserve.
Is culture testing important before starting Avycaz?
Essential — Avycaz should be used for confirmed or highly suspected KPC-producing or other susceptible resistant gram-negative infection. Empiric use for undifferentiated infection promotes resistance and wastes expensive therapy. ID consultation is recommended.
What are the side effects of Avycaz?
Generally well-tolerated. Nausea, vomiting, diarrhea (rule out C. diff), elevated LFTs, cytopenias, hypersensitivity (avoid with beta-lactam allergy), CNS effects at higher doses in renal impairment. Renal dose adjustment is essential to prevent seizures and other CNS effects.
Take Control of Your Medication Costs
Treatment of resistant gram-negative infections should not be delayed by cost. Culture-directed Avycaz can be lifesaving. Our advocacy team is ready — $69.95 per month, or free if we cannot help.
Submit Enrollment Form
Start free by filling out a simple online form.
Receive Welcome Call
Our specialist will contact you for a quick welcome call.
We Manage The Process
Our team handles everything, so you can focus on your health.